Glycation of apolipoprotein E impairs its binding to heparin: identification of the major glycation site.

Shuvaev, V V; Fujii, J; Kawasaki, Y; Itoh, H; Hamaoka, R; Barbier, A; Ziegler, O; Siest, G; Taniguchi, N

Shuvaev, V V; Fujii, J; Kawasaki, Y; Itoh, H; Hamaoka, R; Barbier, A; Ziegler, O; Siest, G; Taniguchi, N.

Affiliation

Shuvaev VV; Department of Biochemistry, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.

Biochim Biophys Acta ; 1454(3): 296-308, 1999 Aug 30.

Article in En | MEDLINE | ID: mdl-10452964

Subject(s)

Apolipoproteins E/metabolism; Heparin/metabolism; Aged; Apolipoproteins E/chemistry; Binding Sites; Chromatography, High Pressure Liquid; Diabetes Mellitus/blood; Enzyme-Linked Immunosorbent Assay; Glucose/chemistry; Glycosylation; Heparin/chemistry; Humans; Hyperglycemia/blood; Lipoproteins, VLDL/blood; Lipoproteins, VLDL/chemistry; Lysine/chemistry; Mass Spectrometry; Peptide Fragments/chemistry; Serine Endopeptidases; Surface Plasmon Resonance

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Database: MEDLINE Main subject: Apolipoproteins E / Heparin Type of study: Diagnostic_studies / Prognostic_studies Limits: Aged / Humans Language: En Year: 1999 Type: Article

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