Optimization of antitumor effect of liposomally encapsulated doxorubicin based on simulations by pharmacokinetic/pharmacodynamic modeling.

Harashima, H; Iida, S; Urakami, Y; Tsuchihashi, M; Kiwada, H

Harashima, H; Iida, S; Urakami, Y; Tsuchihashi, M; Kiwada, H.

Affiliation

Harashima H; Faculty of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima City, Tokushima, Japan. harasima@ph.tokushima-u.ac.jp

J Control Release ; 61(1-2): 93-106, 1999 Aug 27.

Article in En | MEDLINE | ID: mdl-10469906

Subject(s)

Antibiotics, Antineoplastic/administration & dosage; Doxorubicin/administration & dosage; Doxorubicin/pharmacokinetics; Doxorubicin/pharmacology; Humans; Liposomes; Models, Biological

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PubMed Links

Database: MEDLINE Main subject: Doxorubicin / Antibiotics, Antineoplastic Type of study: Prognostic_studies Limits: Humans Language: En Year: 1999 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Doxorubicin / Antibiotics, Antineoplastic Type of study: Prognostic_studies Limits: Humans Language: En Year: 1999 Type: Article