Helix 6 of subdomain III A of human serum albumin is the region primarily photolabeled by ketoprofen, an arylpropionic acid NSAID containing a benzophenone moiety.

Chuang, V T; Kuniyasu, A; Nakayama, H; Matsushita, Y; Hirono, S; Otagiri, M

Chuang, V T; Kuniyasu, A; Nakayama, H; Matsushita, Y; Hirono, S; Otagiri, M.

Affiliation

Chuang VT; Faculty of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto, Japan.

Biochim Biophys Acta ; 1434(1): 18-30, 1999 Sep 14.

Article in En | MEDLINE | ID: mdl-10556556

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/chemistry; Ketoprofen/chemistry; Serum Albumin/genetics; Affinity Labels; Amino Acid Sequence; Chromatography, High Pressure Liquid; Cyanogen Bromide; Indicators and Reagents; Ligands; Models, Molecular; Molecular Sequence Data; Peptide Fragments/chemistry; Serum Albumin/chemistry

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PubMed Links

Database: MEDLINE Main subject: Serum Albumin / Anti-Inflammatory Agents, Non-Steroidal / Ketoprofen Language: En Year: 1999 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Serum Albumin / Anti-Inflammatory Agents, Non-Steroidal / Ketoprofen Language: En Year: 1999 Type: Article