In vitro metabolic products of RWJ-34130, an antiarrythmic agent, in rat liver preparations.

Wu, W N; McKown, L A; Yorgey, K A; Pritchard, J F

Wu, W N; McKown, L A; Yorgey, K A; Pritchard, J F.

Affiliation

Wu WN; Department of Drug Metabolism, The R.W. Johnson Pharmaceutical Research Institute, Spring House, PA 19477-0776, USA.

J Pharm Biomed Anal ; 20(4): 687-95, 1999 Aug.

Article in En | MEDLINE | ID: mdl-10704138

Subject(s)

Amidines/metabolism; Anti-Arrhythmia Agents/metabolism; Imines/metabolism; Indoles/metabolism; Liver/metabolism; Microsomes, Liver/metabolism; Safrole/analogs & derivatives; Amidines/analysis; Amidines/chemistry; Animals; Anti-Arrhythmia Agents/analysis; Anti-Arrhythmia Agents/chemistry; Chromatography, High Pressure Liquid; Imines/analysis; Imines/chemistry; Indoles/analysis; Indoles/chemistry; Male; Mass Spectrometry; Rats; Rats, Wistar; Safrole/analysis; Safrole/metabolism

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Database: MEDLINE Main subject: Safrole / Microsomes, Liver / Amidines / Imines / Indoles / Liver / Anti-Arrhythmia Agents Limits: Animals Language: En Year: 1999 Type: Article

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