Scavenger receptor-mediated delivery of muramyl dipeptide activates antitumor efficacy of macrophages by enhanced secretion of tumor-suppressive cytokines.

Srividya, S; Roy, R P; Basu, S K; Mukhopadhyay, A

Srividya, S; Roy, R P; Basu, S K; Mukhopadhyay, A.

Affiliation

Srividya S; National Institute of Immunology, New Delhi, India.

J Leukoc Biol ; 67(5): 683-90, 2000 May.

Article in En | MEDLINE | ID: mdl-10811009

Subject(s)

Acetylmuramyl-Alanyl-Isoglutamine/pharmacokinetics; Cytokines/metabolism; Macrophage Activation; Macrophages, Peritoneal/immunology; Receptors, Immunologic/physiology; Animals; Cattle; Cells, Cultured; Cytokines/physiology; Cytotoxicity, Immunologic; Endocytosis; Interleukin-10/metabolism; Interleukin-12/metabolism; Kinetics; Macrophages/physiology; Macrophages, Peritoneal/drug effects; Melanoma, Experimental/physiopathology; Mice; Receptors, Scavenger; Serum Albumin, Bovine/pharmacokinetics; Serum Albumin, Bovine/pharmacology; Tumor Cells, Cultured

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Database: MEDLINE Main subject: Receptors, Immunologic / Acetylmuramyl-Alanyl-Isoglutamine / Cytokines / Macrophages, Peritoneal / Macrophage Activation Limits: Animals Language: En Year: 2000 Type: Article

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