Hypermethylation of the death-associated protein (DAP) kinase promoter and aggressiveness in stage I non-small-cell lung cancer.

Tang, X; Khuri, F R; Lee, J J; Kemp, B L; Liu, D; Hong, W K; Mao, L

Tang, X; Khuri, F R; Lee, J J; Kemp, B L; Liu, D; Hong, W K; Mao, L.

Affiliation

Tang X; Molecular Biology Laboratory, Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

J Natl Cancer Inst ; 92(18): 1511-6, 2000 Sep 20.

Article in En | MEDLINE | ID: mdl-10995806

Subject(s)

Calcium-Calmodulin-Dependent Protein Kinases/genetics; Carcinoma, Non-Small-Cell Lung/enzymology; DNA, Neoplasm/metabolism; Lung Neoplasms/enzymology; Promoter Regions, Genetic; Adenocarcinoma/enzymology; Aged; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung/genetics; Carcinoma, Non-Small-Cell Lung/pathology; Carcinoma, Non-Small-Cell Lung/surgery; Carcinoma, Squamous Cell/enzymology; Death-Associated Protein Kinases; Female; Humans; Lung Neoplasms/genetics; Lung Neoplasms/pathology; Lung Neoplasms/surgery; Male; Methylation; Middle Aged; Multivariate Analysis; Neoplasm Staging; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Retrospective Studies

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Database: MEDLINE Main subject: DNA, Neoplasm / Promoter Regions, Genetic / Calcium-Calmodulin-Dependent Protein Kinases / Carcinoma, Non-Small-Cell Lung / Lung Neoplasms Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Year: 2000 Type: Article

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