A human CD46 transgenic pig model system for the study of discordant xenotransplantation.

Diamond, L E; Quinn, C M; Martin, M J; Lawson, J; Platt, J L; Logan, J S

Diamond, L E; Quinn, C M; Martin, M J; Lawson, J; Platt, J L; Logan, J S.

Affiliation

Diamond LE; Nextran, Inc, Princeton, New Jersey 08540, USA.

Transplantation ; 71(1): 132-42, 2001 Jan 15.

Article in En | MEDLINE | ID: mdl-11211178

Subject(s)

Organ Transplantation/physiology; Transplantation, Heterologous; Animals; Animals, Genetically Modified; Antigens, CD/genetics; Complement Inactivator Proteins/genetics; Complement System Proteins/metabolism; Endothelium, Vascular/immunology; Fluorescent Antibody Technique, Direct; Gene Expression; Graft Rejection/prevention & control; Heart Transplantation/immunology; Humans; Immunoglobulin G/metabolism; Immunoglobulin M/metabolism; Membrane Cofactor Protein; Membrane Glycoproteins/genetics; Mice; Mice, Transgenic; Protein Isoforms/genetics; Reverse Transcriptase Polymerase Chain Reaction; Swine

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PubMed Links

Database: MEDLINE Main subject: Transplantation, Heterologous / Organ Transplantation Limits: Animals / Humans Language: En Year: 2001 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Transplantation, Heterologous / Organ Transplantation Limits: Animals / Humans Language: En Year: 2001 Type: Article