TP53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: distinctive spectrum and structural distribution.

Greenblatt, M S; Chappuis, P O; Bond, J P; Hamel, N; Foulkes, W D

Greenblatt, M S; Chappuis, P O; Bond, J P; Hamel, N; Foulkes, W D.

Affiliation

Greenblatt MS; Department of Medicine, Vermont Cancer Center, University of Vermont, Burlington, VT 05405, USA.

Cancer Res ; 61(10): 4092-7, 2001 May 15.

Article in En | MEDLINE | ID: mdl-11358831

Subject(s)

Breast Neoplasms/genetics; Genes, BRCA1/genetics; Genes, p53/genetics; Germ-Line Mutation; Mutation, Missense; Neoplasm Proteins/genetics; Transcription Factors/genetics; BRCA2 Protein; Binding Sites; DNA/metabolism; DNA Mutational Analysis/methods; Female; Humans; Monte Carlo Method; Ovarian Neoplasms/genetics; Protein Structure, Secondary/genetics; Tumor Suppressor Protein p53/chemistry; Tumor Suppressor Protein p53/genetics; Tumor Suppressor Protein p53/metabolism

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Database: MEDLINE Main subject: Transcription Factors / Breast Neoplasms / Genes, p53 / Germ-Line Mutation / Genes, BRCA1 / Mutation, Missense / Neoplasm Proteins Type of study: Health_economic_evaluation / Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Year: 2001 Type: Article

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