Changes in molecular expression of aggrecan and collagen types I, II, and X, insulin-like growth factor-I, and transforming growth factor-beta1 in articular cartilage obtained from horses with naturally acquired osteochondrosis.

Semevolos, S A; Nixon, A J; Brower-Toland, B D

Semevolos, S A; Nixon, A J; Brower-Toland, B D.

Affiliation

Semevolos SA; Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

Am J Vet Res ; 62(7): 1088-94, 2001 Jul.

Article in En | MEDLINE | ID: mdl-11453485

Subject(s)

Cartilage, Articular/metabolism; Collagen/biosynthesis; Extracellular Matrix Proteins; Horse Diseases/metabolism; Insulin-Like Growth Factor I/biosynthesis; Joint Diseases/veterinary; Osteochondritis/veterinary; Proteoglycans/biosynthesis; Transforming Growth Factor beta/biosynthesis; Aggrecans; Animals; Blotting, Northern/veterinary; Cartilage, Articular/pathology; Cartilage, Articular/physiology; Collagen/genetics; Gene Expression Regulation, Developmental; Horse Diseases/genetics; Horse Diseases/pathology; Horses; Immunohistochemistry/veterinary; In Situ Hybridization/veterinary; Insulin-Like Growth Factor I/genetics; Joint Diseases/genetics; Joint Diseases/metabolism; Joint Diseases/pathology; Lectins, C-Type; Osteochondritis/genetics; Osteochondritis/metabolism; Osteochondritis/pathology; Proteoglycans/genetics; RNA/chemistry; RNA/genetics; RNA/isolation & purification; Reverse Transcriptase Polymerase Chain Reaction/veterinary; Transforming Growth Factor beta/genetics; Transforming Growth Factor beta1

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Database: MEDLINE Main subject: Osteochondritis / Proteoglycans / Insulin-Like Growth Factor I / Cartilage, Articular / Extracellular Matrix Proteins / Transforming Growth Factor beta / Collagen / Horse Diseases / Joint Diseases Limits: Animals Language: En Year: 2001 Type: Article

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