Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries.

Hennan, J K; Huang, J; Barrett, T D; Driscoll, E M; Willens, D E; Park, A M; Crofford, L J; Lucchesi, B R

Hennan, J K; Huang, J; Barrett, T D; Driscoll, E M; Willens, D E; Park, A M; Crofford, L J; Lucchesi, B R.

Affiliation

Hennan JK; University of Michigan Medical School, Department of Pharmacology, Ann Arbor 48109-0632, USA.

Circulation ; 104(7): 820-5, 2001 Aug 14.

Article in En | MEDLINE | ID: mdl-11502709

Subject(s)

Coronary Thrombosis/drug therapy; Coronary Vessels/drug effects; Cyclooxygenase Inhibitors/pharmacology; Isoenzymes/antagonists & inhibitors; Vasomotor System/drug effects; Acetylcholine/pharmacology; Animals; Arachidonic Acid/pharmacology; Aspirin/pharmacology; Benzofurans/pharmacology; Blood Flow Velocity/drug effects; Celecoxib; Coronary Circulation/drug effects; Coronary Thrombosis/physiopathology; Coronary Vessels/physiopathology; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors/adverse effects; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Epoprostenol/pharmacology; Platelet Aggregation/drug effects; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides/adverse effects; Sulfonamides/pharmacology; Thromboxane-A Synthase/antagonists & inhibitors; Time Factors; Vasodilation/drug effects; Vasomotor System/physiopathology

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Database: MEDLINE Main subject: Vasomotor System / Coronary Thrombosis / Cyclooxygenase Inhibitors / Coronary Vessels / Isoenzymes Type of study: Prognostic_studies Limits: Animals Language: En Year: 2001 Type: Article

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