Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome.

El Mkadem, S A; Lautier, C; Macari, F; Molinari, N; Lefèbvre, P; Renard, E; Gris, J C; Cros, G; Daurès, J P; Bringer, J; White, M F; Grigorescu, F

El Mkadem, S A; Lautier, C; Macari, F; Molinari, N; Lefèbvre, P; Renard, E; Gris, J C; Cros, G; Daurès, J P; Bringer, J; White, M F; Grigorescu, F.

Affiliation

El Mkadem SA; Molecular Endocrinology Laboratory, Institut Universitaire de Recherche Cilnique, Montpellier, France.

Diabetes ; 50(9): 2164-8, 2001 Sep.

Article in En | MEDLINE | ID: mdl-11522686

Subject(s)

Genetic Variation; Insulin Resistance/genetics; Phosphoproteins/genetics; Polycystic Ovary Syndrome/genetics; Polycystic Ovary Syndrome/physiopathology; Adult; Alleles; Female; Gene Dosage; Genotype; Homeostasis; Humans; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Reference Values

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Database: MEDLINE Main subject: Phosphoproteins / Polycystic Ovary Syndrome / Genetic Variation / Insulin Resistance Type of study: Prognostic_studies Limits: Adult / Female / Humans Language: En Year: 2001 Type: Article

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