Novel monoclonal antibodies against proteolipid protein peptide 139-151 demonstrate demyelination and myelin uptake by macrophages in MS and marmoset EAE lesions.

Laman, J D; Visser, L; Maassen, C B; de Groot, C J; de Jong, L A; 't Hart, B A; van Meurs, M; Schellekens, M M

Laman, J D; Visser, L; Maassen, C B; de Groot, C J; de Jong, L A; 't Hart, B A; van Meurs, M; Schellekens, M M.

Affiliation

Laman JD; Department of Immunology, Erasmus University Rotterdam and University Hospital Dijkzigt, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands. Laman@immu.fgg.eur.nl

J Neuroimmunol ; 119(1): 124-30, 2001 Sep 03.

Article in En | MEDLINE | ID: mdl-11525809

Subject(s)

Encephalomyelitis, Autoimmune, Experimental/metabolism; Encephalomyelitis, Autoimmune, Experimental/pathology; Multiple Sclerosis/metabolism; Multiple Sclerosis/pathology; Myelin Proteolipid Protein/metabolism; Myelin Sheath/metabolism; Myelin Sheath/pathology; Peptide Fragments/metabolism; Animals; Antibodies, Monoclonal; Callithrix; Demyelinating Diseases/metabolism; Demyelinating Diseases/pathology; Female; Humans; Macrophages/metabolism; Mice; Mice, Inbred Strains; Reference Values

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Database: MEDLINE Main subject: Peptide Fragments / Myelin Proteolipid Protein / Encephalomyelitis, Autoimmune, Experimental / Multiple Sclerosis / Myelin Sheath Limits: Animals / Female / Humans Language: En Year: 2001 Type: Article

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