Neuroprotective effect of immunosuppressant FK506 in transient focal ischemia in rat: therapeutic time window for FK506 in transient focal ischemia.

Arii, T; Kamiya, T; Arii, K; Ueda, M; Nito, C; Katsura, K I; Katayama, Y

Arii, T; Kamiya, T; Arii, K; Ueda, M; Nito, C; Katsura, K I; Katayama, Y.

Affiliation

Arii T; The Second Department of Internal Medicine, Nippon Medical School, Tokyo, Japan. ariitaka@nms.ac.jp

Neurol Res ; 23(7): 755-60, 2001 Oct.

Article in En | MEDLINE | ID: mdl-11680517

Subject(s)

Brain Ischemia/drug therapy; Brain/drug effects; Immunosuppressive Agents/pharmacology; Neurons/drug effects; Neuroprotective Agents/pharmacology; Reperfusion Injury/drug therapy; Tacrolimus/pharmacology; Animals; Blood Glucose/drug effects; Blood Glucose/physiology; Brain/metabolism; Brain/physiopathology; Brain Edema/drug therapy; Brain Edema/metabolism; Brain Edema/physiopathology; Brain Ischemia/metabolism; Brain Ischemia/physiopathology; Cardiovascular Physiological Phenomena/drug effects; Cerebral Infarction/drug therapy; Cerebral Infarction/metabolism; Cerebral Infarction/physiopathology; Drug Administration Schedule; Infarction, Middle Cerebral Artery/drug therapy; Infarction, Middle Cerebral Artery/metabolism; Infarction, Middle Cerebral Artery/physiopathology; Male; Neurons/metabolism; Rats; Rats, Sprague-Dawley; Reperfusion Injury/metabolism; Reperfusion Injury/physiopathology; Treatment Outcome

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Database: MEDLINE Main subject: Brain / Reperfusion Injury / Brain Ischemia / Tacrolimus / Neuroprotective Agents / Immunosuppressive Agents / Neurons Limits: Animals Language: En Year: 2001 Type: Article

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