Mrc1 transduces signals of DNA replication stress to activate Rad53.

Alcasabas, A A; Osborn, A J; Bachant, J; Hu, F; Werler, P J; Bousset, K; Furuya, K; Diffley, J F; Carr, A M; Elledge, S J

Alcasabas, A A; Osborn, A J; Bachant, J; Hu, F; Werler, P J; Bousset, K; Furuya, K; Diffley, J F; Carr, A M; Elledge, S J.

Affiliation

Alcasabas AA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

Nat Cell Biol ; 3(11): 958-65, 2001 Nov.

Article in En | MEDLINE | ID: mdl-11715016

Subject(s)

DNA Replication; DNA, Fungal/biosynthesis; Fungal Proteins/metabolism; Protein Serine-Threonine Kinases/metabolism; Saccharomyces cerevisiae Proteins/metabolism; Signal Transduction; Amino Acid Sequence; Animals; Cell Cycle Proteins/metabolism; Checkpoint Kinase 2; Enzyme Activation; Fungal Proteins/genetics; Genes, Fungal; Humans; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Protein Kinases/metabolism; S Phase; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Saccharomyces cerevisiae Proteins/genetics; Schizosaccharomyces; Schizosaccharomyces pombe Proteins

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Database: MEDLINE Main subject: DNA, Fungal / Fungal Proteins / Signal Transduction / Protein Serine-Threonine Kinases / Saccharomyces cerevisiae Proteins / DNA Replication Limits: Animals / Humans Language: En Year: 2001 Type: Article

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