High NaCl intake decreases both flow-induced dilation and pressure-induced myogenic tone in resistance arteries from normotensive rats: involvement of cyclooxygenase-2.

Matrougui, K; Loufrani, L; Lévy, B I; Henrion, D

Matrougui, K; Loufrani, L; Lévy, B I; Henrion, D.

Affiliation

Matrougui K; Institute of Health National and Medical Research (INSERM) U 541, IFR 6 Circulation Lariboisière, University of Paris VII, France. matrougui9@hotmail.com

Pharmacol Toxicol ; 89(4): 183-7, 2001 Oct.

Article in En | MEDLINE | ID: mdl-11881968

Subject(s)

Arginine/analogs & derivatives; Blood Pressure/physiology; Isoenzymes/metabolism; Mesenteric Arteries/physiology; Muscle, Smooth, Vascular/physiology; Prostaglandin-Endoperoxide Synthases/metabolism; Sodium Chloride, Dietary/administration & dosage; Vasodilation/physiology; Animals; Arginine/pharmacology; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors/pharmacology; Disease Models, Animal; Endothelium, Vascular/drug effects; Endothelium, Vascular/enzymology; Indomethacin/pharmacology; Isoenzymes/antagonists & inhibitors; Mesenteric Arteries/drug effects; Muscle, Smooth, Vascular/drug effects; Nitric Oxide Synthase/antagonists & inhibitors; Nitric Oxide Synthase/metabolism; Nitric Oxide Synthase Type III; Nitrobenzenes/pharmacology; Rats; Rats, Inbred WKY; Regional Blood Flow/physiology; Sodium Chloride, Dietary/pharmacology; Sulfonamides/pharmacology; Vasodilation/drug effects

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Database: MEDLINE Main subject: Arginine / Vasodilation / Blood Pressure / Prostaglandin-Endoperoxide Synthases / Sodium Chloride, Dietary / Isoenzymes / Mesenteric Arteries / Muscle, Smooth, Vascular Limits: Animals Language: En Year: 2001 Type: Article

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