The presence of both the amino- and carboxyl-terminal domains in the AR is essential for the completion of a transcriptionally active form with coactivators and intranuclear compartmentalization common to the steroid hormone receptors: a three-dimensional imaging study.

Saitoh, Masayuki; Takayanagi, Ryoichi; Goto, Kiminobu; Fukamizu, Akiyoshi; Tomura, Arihiro; Yanase, Toshihiko; Nawata, Hajime

Saitoh, Masayuki; Takayanagi, Ryoichi; Goto, Kiminobu; Fukamizu, Akiyoshi; Tomura, Arihiro; Yanase, Toshihiko; Nawata, Hajime.

Affiliation

Saitoh M; Department of Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.

Mol Endocrinol ; 16(4): 694-706, 2002 Apr.

Article in En | MEDLINE | ID: mdl-11923466

Subject(s)

Receptors, Androgen/physiology; Transcriptional Activation; Animals; COS Cells; Cell Compartmentation; Dihydrotestosterone/metabolism; Fluorescent Dyes/metabolism; Genes, Reporter; Green Fluorescent Proteins; Histone Acetyltransferases; Humans; Imaging, Three-Dimensional; Luciferases/genetics; Luminescent Proteins/metabolism; Male; Microscopy, Fluorescence; Nuclear Receptor Coactivator 1; Nuclear Receptor Coactivator 2; Receptors, Androgen/chemistry; Receptors, Androgen/genetics; Structure-Activity Relationship; Transcription Factors/metabolism; Transfection; Tumor Cells, Cultured

Search on Google

XML

PubMed Links

Database: MEDLINE Main subject: Receptors, Androgen / Transcriptional Activation Limits: Animals / Humans / Male Language: En Year: 2002 Type: Article

Search on Google

XML

PubMed Links

Database: MEDLINE Main subject: Receptors, Androgen / Transcriptional Activation Limits: Animals / Humans / Male Language: En Year: 2002 Type: Article