Gadolinium chloride pretreatment prevents cadmium chloride-induced liver damage in both wild-type and MT-null mice.

Harstad, Eric B; Klaassen, Curtis D

Harstad, Eric B; Klaassen, Curtis D.

Affiliation

Harstad EB; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, 66160-7140

Toxicol Appl Pharmacol ; 180(3): 178-85, 2002 May 01.

Article in En | MEDLINE | ID: mdl-12009857

Subject(s)

Anti-Inflammatory Agents/therapeutic use; Cadmium Chloride/antagonists & inhibitors; Chemical and Drug Induced Liver Injury/prevention & control; Gadolinium/therapeutic use; Kupffer Cells/drug effects; Metallothionein/biosynthesis; Animals; Cadmium Chloride/toxicity; Chemical and Drug Induced Liver Injury/pathology; Dose-Response Relationship, Drug; Kupffer Cells/metabolism; Male; Mice

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Database: MEDLINE Main subject: Cadmium Chloride / Chemical and Drug Induced Liver Injury / Gadolinium / Kupffer Cells / Metallothionein / Anti-Inflammatory Agents Limits: Animals Language: En Year: 2002 Type: Article

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