Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

Grenier, Jill M; Wang, Lin; Manji, Gulam A; Huang, Waan Jeng; Al-Garawi, Amal; Kelly, Roxanne; Carlson, Adam; Merriam, Sarah; Lora, Jose M; Briskin, Michael; DiStefano, Peter S; Bertin, John

Grenier, Jill M; Wang, Lin; Manji, Gulam A; Huang, Waan Jeng; Al-Garawi, Amal; Kelly, Roxanne; Carlson, Adam; Merriam, Sarah; Lora, Jose M; Briskin, Michael; DiStefano, Peter S; Bertin, John.

Affiliation

Grenier JM; Millennium Pharmaceuticals Inc., 75 Sidney Street, Cambridge, MA 02139, USA. bertin@mpi.com

FEBS Lett ; 530(1-3): 73-8, 2002 Oct 23.

Article in En | MEDLINE | ID: mdl-12387869

Subject(s)

Carrier Proteins/physiology; Caspase 1/physiology; Intracellular Signaling Peptides and Proteins; NF-kappa B/physiology; Amino Acid Sequence; Animals; Base Sequence; COS Cells; Carrier Proteins/chemistry; Carrier Proteins/genetics; Carrier Proteins/metabolism; Cell Line; DNA Primers; Enzyme Activation; Humans; Leukocytes/metabolism; Molecular Sequence Data; Signal Transduction

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Database: MEDLINE Main subject: Carrier Proteins / NF-kappa B / Caspase 1 / Intracellular Signaling Peptides and Proteins Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Limits: Animals / Humans Language: En Year: 2002 Type: Article

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