Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents.

Antonini, Ippolito; Polucci, Paolo; Magnano, Amelia; Gatto, Barbara; Palumbo, Manlio; Menta, Ernesto; Pescalli, Nicoletta; Martelli, Sante

Antonini, Ippolito; Polucci, Paolo; Magnano, Amelia; Gatto, Barbara; Palumbo, Manlio; Menta, Ernesto; Pescalli, Nicoletta; Martelli, Sante.

Affiliation

Antonini I; Department of Chemical Sciences, University of Camerino, Via S Agostino 1, 62032 Camerino, Italy. ippolito.antonini@unicam.it

J Med Chem ; 46(14): 3109-15, 2003 Jul 03.

Article in En | MEDLINE | ID: mdl-12825949

Subject(s)

Acridines/chemical synthesis; Antineoplastic Agents/chemical synthesis; Intercalating Agents/chemical synthesis; Acridines/chemistry; Acridines/pharmacology; Antineoplastic Agents/chemistry; Antineoplastic Agents/pharmacology; Cell Division/drug effects; DNA/chemistry; Drug Design; Drug Screening Assays, Antitumor; Electrophoresis, Agar Gel; Fluorometry; Humans; Intercalating Agents/chemistry; Intercalating Agents/pharmacology; Structure-Activity Relationship; Tumor Cells, Cultured

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Database: MEDLINE Main subject: Acridines / Intercalating Agents / Antineoplastic Agents Limits: Humans Language: En Year: 2003 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Acridines / Intercalating Agents / Antineoplastic Agents Limits: Humans Language: En Year: 2003 Type: Article