Adenosine Triphosphatases/chemistry; Calcium-Binding Proteins/metabolism; Carrier Proteins/chemistry; Carrier Proteins/metabolism; Nuclear Proteins/chemistry; Repressor Proteins/chemistry; Saccharomyces cerevisiae Proteins/chemistry; ATPases Associated with Diverse Cellular Activities; Amino Acid Sequence; Calcium-Binding Proteins/physiology; Carrier Proteins/physiology; Cell Cycle Proteins; Cell Line; Cytoplasm/metabolism; DNA, Complementary/metabolism; Endocytosis; Endosomal Sorting Complexes Required for Transport; Endosomes/metabolism; Epidermal Growth Factor/metabolism; Genes, Dominant; Glutathione Transferase/metabolism; HeLa Cells; Humans; Microscopy, Fluorescence; Models, Genetic; Molecular Sequence Data; Phylogeny; Plasmids/metabolism; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins/metabolism; Sequence Homology, Amino Acid; Transfection; Two-Hybrid System Techniques; Ubiquitin/metabolism; Vacuolar Proton-Translocating ATPases; Vesicular Transport Proteins