Repeated stimulation of D1 dopamine receptors causes time-dependent alterations in the sensitivity of both D1 and D2 dopamine receptors within the rat striatum.

Hu, X T; Brooderson, R J; White, F J

Hu, X T; Brooderson, R J; White, F J.

Affiliation

Hu XT; Department of Psychiatry, Wayne State University School of Medicine, Lafayette Clinic, Detroit, MI 48207.

Neuroscience ; 50(1): 137-47, 1992 Sep.

Article in En | MEDLINE | ID: mdl-1357592

Subject(s)

2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/pharmacology; Corpus Striatum/physiology; Dopamine Agents/pharmacology; Ergolines/pharmacology; Grooming/drug effects; Neurons/physiology; Receptors, Dopamine D1/physiology; Receptors, Dopamine D2/physiology; Stereotyped Behavior/drug effects; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine/administration & dosage; Animals; Corpus Striatum/drug effects; Dopamine Agents/administration & dosage; Drug Tolerance; Ergolines/administration & dosage; Iontophoresis; Male; Neurons/drug effects; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1/drug effects; Receptors, Dopamine D2/drug effects; Reference Values; Time Factors

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Database: MEDLINE Main subject: Stereotyped Behavior / Dopamine Agents / 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine / Receptors, Dopamine D2 / Receptors, Dopamine D1 / Corpus Striatum / Ergolines / Grooming / Neurons Type of study: Diagnostic_studies / Etiology_studies Limits: Animals Language: En Year: 1992 Type: Article

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