Construction of a 7-aminocephalosporanic acid (7ACA) biosynthetic operon and direct production of 7ACA in Acremonium chrysogenum.

Isogai, T; Fukagawa, M; Aramori, I; Iwami, M; Kojo, H; Ono, T; Ueda, Y; Kohsaka, M; Imanaka, H

Isogai, T; Fukagawa, M; Aramori, I; Iwami, M; Kojo, H; Ono, T; Ueda, Y; Kohsaka, M; Imanaka, H.

Affiliation

Isogai T; Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd, Ibaraki, Japan.

Biotechnology (N Y) ; 9(2): 188-91, 1991 Feb.

Article in En | MEDLINE | ID: mdl-1369453

Subject(s)

Acremonium/genetics; Cephalosporins/biosynthesis; Operon/genetics; Acremonium/enzymology; Base Sequence; Blotting, Southern; Cloning, Molecular; D-Amino-Acid Oxidase/genetics; DNA, Bacterial/genetics; DNA, Fungal/genetics; Fusarium/enzymology; Fusarium/genetics; Molecular Sequence Data; Penicillin Amidase/genetics; Pseudomonas/enzymology; Pseudomonas/genetics; Serine Endopeptidases/genetics; Transformation, Bacterial

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