Acute experimental unilateral orchitis in the rabbit and its effect on fertility.
Int Urol Nephrol
; 24(3): 291-7, 1992.
Article
in En
| MEDLINE
| ID: mdl-1399386
ABSTRACT
We examined the nature of contralateral damage following unilateral orchitis to see if an immunologically mediated mechanism was present. Experimentally induced orchitis in 18 white New Zealand rabbits were examined and compared to 20 in the control groups. Serum antisperm antibody presence and bilateral testicular biopsies (Johansen biopsy score, mean seminiferous tubule diameter) were examined and pregnancy rates were noted. Acute orchitis seemed to be a causative factor in production of antisperm antibody and the presence of antisperm antibody caused histologic changes in contralateral testicles and therefore impaired fertility.
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Database:
MEDLINE
Main subject:
Orchitis
/
Infertility, Male
Type of study:
Etiology_studies
/
Prognostic_studies
Limits:
Animals
/
Pregnancy
Language:
En
Year:
1992
Type:
Article