Inhibitors of lipoprotein(a) assembly.

Sexton, Karen E; Lee, Helen T; Massa, Mark; Padia, Janak; Patt, William C; Liao, Peggy; Pontrello, Jason K; Roth, Bruce D; Spahr, Mark A; Ramharack, Randy

Sexton, Karen E; Lee, Helen T; Massa, Mark; Padia, Janak; Patt, William C; Liao, Peggy; Pontrello, Jason K; Roth, Bruce D; Spahr, Mark A; Ramharack, Randy.

Affiliation

Sexton KE; Department of Medicinal Chemistry, Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, MI 48105, USA.

Bioorg Med Chem ; 11(22): 4827-45, 2003 Nov 03.

Article in En | MEDLINE | ID: mdl-14556799

Subject(s)

Amino Acids/pharmacology; Lipoprotein(a)/antagonists & inhibitors; Sulfonamides/pharmacology; Amino Acids/chemistry; Animals; Cell Line; Dose-Response Relationship, Drug; Haplorhini; Humans; Inhibitory Concentration 50; Lipoprotein(a)/biosynthesis; Lipoprotein(a)/blood; Mice; Mice, Transgenic; Structure-Activity Relationship; Sulfonamides/chemistry

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Database: MEDLINE Main subject: Sulfonamides / Lipoprotein(a) / Amino Acids Limits: Animals / Humans Language: En Year: 2003 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Sulfonamides / Lipoprotein(a) / Amino Acids Limits: Animals / Humans Language: En Year: 2003 Type: Article