Apolipoprotein E and beta-amyloid (1-42) regulation of glycogen synthase kinase-3beta.

Cedazo-Mínguez, A; Popescu, B O; Blanco-Millán, J M; Akterin, S; Pei, J-J; Winblad, B; Cowburn, R F

Cedazo-Mínguez, A; Popescu, B O; Blanco-Millán, J M; Akterin, S; Pei, J-J; Winblad, B; Cowburn, R F.

Affiliation

Cedazo-Mínguez A; Neurotec, Section for Experimental Geriatrics, Karolinska Institutet, NOVUM, KFC, plan 4, S-141 86 Huddinge, Sweden. Angel.Cedazo-Mínguez@neurotec.ki.se

J Neurochem ; 87(5): 1152-64, 2003 Dec.

Article in En | MEDLINE | ID: mdl-14622095

Subject(s)

Amyloid beta-Peptides/pharmacology; Apolipoproteins E/pharmacology; Glycogen Synthase Kinase 3/drug effects; Glycogen Synthase Kinase 3/metabolism; Neuroblastoma/metabolism; Peptide Fragments/pharmacology; Protein Serine-Threonine Kinases; Apolipoprotein E3; Apolipoprotein E4; Apolipoproteins E/chemistry; Calcium/metabolism; Caspase 3; Caspases/metabolism; Cell Line, Tumor; Cell Survival/drug effects; Culture Media, Serum-Free/chemistry; Cytoskeletal Proteins/metabolism; Enzyme Activation/drug effects; Glycogen Synthase Kinase 3/chemistry; Glycogen Synthase Kinase 3 beta; Humans; Neuroblastoma/chemistry; Neuroblastoma/drug therapy; Phosphorylation/drug effects; Protein Isoforms/chemistry; Protein Isoforms/pharmacology; Protein Kinase C/drug effects; Protein Kinase C/metabolism; Protein Kinase C-alpha; Protein Transport/drug effects; Proto-Oncogene Proteins/drug effects; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-akt; Trans-Activators/metabolism; beta Catenin

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PubMed Links

Database: MEDLINE Main subject: Apolipoproteins E / Peptide Fragments / Amyloid beta-Peptides / Protein Serine-Threonine Kinases / Glycogen Synthase Kinase 3 / Neuroblastoma Limits: Humans Language: En Year: 2003 Type: Article

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