[Correlations among mood disorder, serum interleukin-2 and interleukin-6 in patients with burning mouth syndrome].

ABSTRACT

OBJECTIVE: To examine serum IL-2 and IL-6 levels in BMS patients with or without depression and make clear the relationship between serum IL-2, IL-6 and mood disorder. METHODS: Serum IL-2 and IL-6 were examined in 48 BMS patients by means of ELISA. The Hamilton Depression Rating Scale (HDRS) was used to evaluate the depressive symptomatology. RESULTS: There was no significant difference in serum IL-2 and IL-6 among BMS patients with or without depression. Mood disorder was not correlated to serum IL-2 and IL-6, but positively correlated to pain levels. CONCLUSION: Depression status may not influence serum IL-2 and IL-6 levels significantly, but it has a relationship with BMS. The HDRS can be used to determine depression status in BMS patients in order to help clinical treatment.