Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2.

Lorenz, Kristina; Lohse, Martin J; Quitterer, Ursula

Lorenz, Kristina; Lohse, Martin J; Quitterer, Ursula.

Affiliation

Lorenz K; Institut für Pharmakologie und Toxikologie, Versbacher Strasse 9, D-97078 Würzburg, Germany.

Nature ; 426(6966): 574-9, 2003 Dec 04.

Article in En | MEDLINE | ID: mdl-14654844

Subject(s)

Androgen-Binding Protein; Carrier Proteins/metabolism; Cyclic AMP-Dependent Protein Kinases/antagonists & inhibitors; Enzyme Inhibitors/metabolism; Protein Kinase C/metabolism; Proto-Oncogene Proteins c-raf/antagonists & inhibitors; Animals; Brain/metabolism; Carrier Proteins/genetics; Cell Line; Cyclic AMP-Dependent Protein Kinases/genetics; Cyclic AMP-Dependent Protein Kinases/metabolism; G-Protein-Coupled Receptor Kinase 2; G-Protein-Coupled Receptor Kinase 3; Humans; Mice; Myocytes, Cardiac/metabolism; Phosphatidylethanolamine Binding Protein; Phospholipid Transfer Proteins; Phosphorylation; Precipitin Tests; Prostatein; Protein Binding; Proto-Oncogene Proteins c-raf/genetics; Proto-Oncogene Proteins c-raf/metabolism; RNA Interference; Rats; Secretoglobins; Signal Transduction; Substrate Specificity; Uteroglobin; beta-Adrenergic Receptor Kinases

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Database: MEDLINE Main subject: Protein Kinase C / Carrier Proteins / Cyclic AMP-Dependent Protein Kinases / Proto-Oncogene Proteins c-raf / Enzyme Inhibitors / Androgen-Binding Protein Limits: Animals / Humans Language: En Year: 2003 Type: Article

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