Evidence that dynorphin plays a major role in mediating progesterone negative feedback on gonadotropin-releasing hormone neurons in sheep.

Goodman, Robert L; Coolen, Lique M; Anderson, Greg M; Hardy, Steven L; Valent, Miro; Connors, John M; Fitzgerald, Maureen E; Lehman, Michael N

Goodman, Robert L; Coolen, Lique M; Anderson, Greg M; Hardy, Steven L; Valent, Miro; Connors, John M; Fitzgerald, Maureen E; Lehman, Michael N.

Affiliation

Goodman RL; Department of Physiology and Pharmacology, Health Sciences Center North, Medical Center Drive, Morgantown, West Virginia 26506-9229, USA. bgoodman@hsc.wvu.edu

Endocrinology ; 145(6): 2959-67, 2004 Jun.

Article in En | MEDLINE | ID: mdl-14988383

Subject(s)

Dynorphins/physiology; Feedback, Physiological; Gonadotropin-Releasing Hormone/metabolism; Hypothalamus, Middle/physiology; Neurons/physiology; Progesterone/physiology; Animals; Dynorphins/metabolism; Endorphins/physiology; Female; Hypothalamus, Middle/cytology; Luteinizing Hormone/antagonists & inhibitors; Preoptic Area/physiology; Receptors, Opioid, kappa/physiology; Receptors, Opioid, mu/physiology; Sheep; Synapses/physiology; beta-Endorphin/metabolism

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Database: MEDLINE Main subject: Progesterone / Dynorphins / Gonadotropin-Releasing Hormone / Feedback, Physiological / Hypothalamus, Middle / Neurons Limits: Animals Language: En Year: 2004 Type: Article

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