Transcriptional basis of KRAS oncogene-mediated cellular transformation in ovarian epithelial cells.

Tchernitsa, Oleg I; Sers, Christine; Zuber, Johannes; Hinzmann, Bernd; Grips, Martin; Schramme, Anja; Lund, Per; Schwendel, Anke; Rosenthal, André; Schäfer, Reinhold

Tchernitsa, Oleg I; Sers, Christine; Zuber, Johannes; Hinzmann, Bernd; Grips, Martin; Schramme, Anja; Lund, Per; Schwendel, Anke; Rosenthal, André; Schäfer, Reinhold.

Affiliation

Tchernitsa OI; Laboratory of Molecular Tumor Pathology, Institute of Pathology, Charité, Humboldt-University Berlin, Schumannstr. 20/21, D-10117 Berlin, Germany.

Oncogene ; 23(26): 4536-55, 2004 Jun 03.

Article in En | MEDLINE | ID: mdl-15064704

Subject(s)

Cell Transformation, Neoplastic/genetics; Genes, ras; Ovary/pathology; Transcription, Genetic; Animals; Chromones/pharmacology; Enzyme Inhibitors/pharmacology; Epithelial Cells/drug effects; Epithelial Cells/metabolism; Epithelial Cells/pathology; Female; Flavonoids/pharmacology; Gene Expression Regulation, Neoplastic; Mitogen-Activated Protein Kinases; Morpholines/pharmacology; Ovary/drug effects; Ovary/physiology; Phosphatidylinositol 3-Kinases/metabolism; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-fos/drug effects; Proto-Oncogene Proteins c-fos/genetics; Proto-Oncogene Proteins c-raf/drug effects; Proto-Oncogene Proteins c-raf/metabolism; Rats; Signal Transduction

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Database: MEDLINE Main subject: Ovary / Transcription, Genetic / Cell Transformation, Neoplastic / Genes, ras Type of study: Prognostic_studies Limits: Animals Language: En Year: 2004 Type: Article

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