Phase 1 trial study of 131I-labeled chimeric 81C6 monoclonal antibody for the treatment of patients with non-Hodgkin lymphoma.

Rizzieri, David A; Akabani, Gamal; Zalutsky, Michael R; Coleman, R Edward; Metzler, Scott D; Bowsher, James E; Toaso, Bonnie; Anderson, Elizabeth; Lagoo, Anand; Clayton, Steve; Pegram, Charles N; Moore, Joseph O; Gockerman, Jon P; DeCastro, Carlos; Gasparetto, Cristina; Chao, Nelson J; Bigner, Darell D

Rizzieri, David A; Akabani, Gamal; Zalutsky, Michael R; Coleman, R Edward; Metzler, Scott D; Bowsher, James E; Toaso, Bonnie; Anderson, Elizabeth; Lagoo, Anand; Clayton, Steve; Pegram, Charles N; Moore, Joseph O; Gockerman, Jon P; DeCastro, Carlos; Gasparetto, Cristina; Chao, Nelson J; Bigner, Darell D.

Affiliation

Rizzieri DA; Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. rizzi003@mc.duke.edu

Blood ; 104(3): 642-8, 2004 Aug 01.

Article in En | MEDLINE | ID: mdl-15100153

Subject(s)

Antibodies, Monoclonal/toxicity; Iodine Radioisotopes/toxicity; Lymphoma, Non-Hodgkin/radiotherapy; Animals; Antibodies, Monoclonal/pharmacokinetics; Biological Transport; Biopsy; Bone Marrow/pathology; Female; Humans; Immunotoxins/pharmacokinetics; Immunotoxins/toxicity; Iodine Radioisotopes/pharmacokinetics; Lymph Nodes/pathology; Lymphoma, Non-Hodgkin/pathology; Male; Mice; Patient Selection; Tenascin/analysis; Tissue Distribution; Tomography, X-Ray Computed

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Database: MEDLINE Main subject: Lymphoma, Non-Hodgkin / Iodine Radioisotopes / Antibodies, Monoclonal Limits: Animals / Female / Humans / Male Language: En Year: 2004 Type: Article

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