The androgen receptor ligand-binding domain stabilizes DNA binding in living cells.

Farla, Pascal; Hersmus, Remko; Geverts, Bart; Mari, Pierre O; Nigg, Alex L; Dubbink, Hendrikus J; Trapman, Jan; Houtsmuller, Adriaan B

Farla, Pascal; Hersmus, Remko; Geverts, Bart; Mari, Pierre O; Nigg, Alex L; Dubbink, Hendrikus J; Trapman, Jan; Houtsmuller, Adriaan B.

Affiliation

Farla P; Department of Pathology, Josephine Nefkens Institute, Erasmus MC, University Medical Center Rotterdam, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.

J Struct Biol ; 147(1): 50-61, 2004 Jul.

Article in En | MEDLINE | ID: mdl-15109605

Subject(s)

DNA/metabolism; Receptors, Androgen/metabolism; Active Transport, Cell Nucleus/physiology; Cell Line; Computer Simulation; Fluorescence Recovery After Photobleaching; Humans; Ligands; Macromolecular Substances; Metribolone/metabolism; Promoter Regions, Genetic; Protein Binding; Protein Structure, Tertiary; Receptors, Androgen/chemistry; Receptors, Androgen/genetics; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Transcriptional Activation

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Database: MEDLINE Main subject: DNA / Receptors, Androgen Type of study: Prognostic_studies Limits: Humans Language: En Year: 2004 Type: Article

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PubMed Links

Database: MEDLINE Main subject: DNA / Receptors, Androgen Type of study: Prognostic_studies Limits: Humans Language: En Year: 2004 Type: Article