Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease.

Hollenbach, Eike; Neumann, Manfred; Vieth, Michael; Roessner, Albert; Malfertheiner, Peter; Naumann, Michael

Hollenbach, Eike; Neumann, Manfred; Vieth, Michael; Roessner, Albert; Malfertheiner, Peter; Naumann, Michael.

Affiliation

Hollenbach E; Institute of Experimental Internal Medicine, Otto-von-Guericke-University, Magdeburg, Germany.

FASEB J ; 18(13): 1550-2, 2004 Oct.

Article in En | MEDLINE | ID: mdl-15289440

Subject(s)

Imidazoles/pharmacology; Imidazoles/therapeutic use; Inflammatory Bowel Diseases/drug therapy; NF-kappa B/antagonists & inhibitors; Protein Kinases/metabolism; Pyridines/pharmacology; Pyridines/therapeutic use; Signal Transduction/drug effects; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors; Animals; Colitis, Ulcerative/drug therapy; Colitis, Ulcerative/pathology; Cytokines/antagonists & inhibitors; Cytokines/metabolism; Disease Models, Animal; Inflammation Mediators/antagonists & inhibitors; Inflammation Mediators/metabolism; Inflammatory Bowel Diseases/chemically induced; Inflammatory Bowel Diseases/metabolism; Inflammatory Bowel Diseases/pathology; Mice; Mice, Inbred BALB C; NF-kappa B/metabolism; Plasma Cells; Receptor-Interacting Protein Serine-Threonine Kinase 2; Receptor-Interacting Protein Serine-Threonine Kinases; p38 Mitogen-Activated Protein Kinases/metabolism

Search on Google

XML

PubMed Links

Database: MEDLINE Main subject: Protein Kinases / Pyridines / Inflammatory Bowel Diseases / Signal Transduction / NF-kappa B / P38 Mitogen-Activated Protein Kinases / Imidazoles Type of study: Prognostic_studies Limits: Animals Language: En Year: 2004 Type: Article

Search on Google

XML

PubMed Links