Delta(9)-THC-induced cognitive deficits in mice are reversed by the GABA(A) antagonist bicuculline.

Varvel, S A; Anum, E; Niyuhire, F; Wise, L E; Lichtman, A H

Varvel, S A; Anum, E; Niyuhire, F; Wise, L E; Lichtman, A H.

Affiliation

Varvel SA; Department of Pharmacology, VCU, PO Box 980613, Richmond, VA 23298, USA. savarvel@vcu.edu

Psychopharmacology (Berl) ; 178(2-3): 317-27, 2005 Mar.

Article in En | MEDLINE | ID: mdl-15322725

Subject(s)

Bicuculline/pharmacology; Dronabinol/toxicity; GABA-A Receptor Antagonists; Marijuana Abuse/psychology; Mental Recall/drug effects; Animals; Baclofen/pharmacology; Brain/drug effects; GABA-A Receptor Agonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Maze Learning/drug effects; Memory, Short-Term/drug effects; Mice; Mice, Inbred C57BL; Muscimol/toxicity; Organophosphorus Compounds/pharmacology; Phenotype; Receptor, Cannabinoid, CB1/antagonists & inhibitors; Receptor, Cannabinoid, CB1/genetics

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Database: MEDLINE Main subject: Mental Recall / Dronabinol / Bicuculline / Marijuana Abuse / GABA-A Receptor Antagonists Limits: Animals Language: En Year: 2005 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Mental Recall / Dronabinol / Bicuculline / Marijuana Abuse / GABA-A Receptor Antagonists Limits: Animals Language: En Year: 2005 Type: Article