Effective knock down of very high ABCG2 expression by a hammerhead ribozyme.

Kowalski, Petra; Farley, Kate M; Lage, Hermann; Schneider, Erasmus

Kowalski, Petra; Farley, Kate M; Lage, Hermann; Schneider, Erasmus.

Affiliation

Kowalski P; Wadsworth Center, Empire State Plaza, Albany, NY 12201, USA.

Anticancer Res ; 24(4): 2231-5, 2004.

Article in En | MEDLINE | ID: mdl-15330166

Subject(s)

ATP-Binding Cassette Transporters/antagonists & inhibitors; ATP-Binding Cassette Transporters/biosynthesis; Breast Neoplasms/metabolism; Neoplasm Proteins/antagonists & inhibitors; Neoplasm Proteins/biosynthesis; RNA, Catalytic/metabolism; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters/genetics; Antineoplastic Agents/pharmacology; Breast Neoplasms/drug therapy; Breast Neoplasms/enzymology; Breast Neoplasms/genetics; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Methotrexate/pharmacology; Mitoxantrone/pharmacology; Neoplasm Proteins/genetics; RNA, Catalytic/biosynthesis; RNA, Catalytic/genetics; Reverse Transcriptase Polymerase Chain Reaction; Topotecan/pharmacology; Transfection

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PubMed Links

Database: MEDLINE Main subject: Breast Neoplasms / RNA, Catalytic / ATP-Binding Cassette Transporters / Neoplasm Proteins Limits: Humans Language: En Year: 2004 Type: Article

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XML

PubMed Links

Database: MEDLINE Main subject: Breast Neoplasms / RNA, Catalytic / ATP-Binding Cassette Transporters / Neoplasm Proteins Limits: Humans Language: En Year: 2004 Type: Article