Cdc7 inhibition reveals a p53-dependent replication checkpoint that is defective in cancer cells.

Montagnoli, Alessia; Tenca, Pierluigi; Sola, Francesco; Carpani, Daniela; Brotherton, Deborah; Albanese, Clara; Santocanale, Corrado

Montagnoli, Alessia; Tenca, Pierluigi; Sola, Francesco; Carpani, Daniela; Brotherton, Deborah; Albanese, Clara; Santocanale, Corrado.

Affiliation

Montagnoli A; Department of Biology, Nerviano Medical Science, Nerviano, Italy.

Cancer Res ; 64(19): 7110-6, 2004 Oct 01.

Article in En | MEDLINE | ID: mdl-15466207

Subject(s)

Cell Cycle Proteins/antagonists & inhibitors; Protein Serine-Threonine Kinases/antagonists & inhibitors; S Phase/physiology; Tumor Suppressor Protein p53/physiology; Apoptosis/physiology; Cell Cycle/physiology; Cell Cycle Proteins/genetics; Disease Progression; Down-Regulation; HeLa Cells; Humans; Protein Serine-Threonine Kinases/deficiency; Protein Serine-Threonine Kinases/genetics; RNA, Small Interfering/genetics; Transfection

Search on Google

XML

PubMed Links

Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / S Phase / Protein Serine-Threonine Kinases / Cell Cycle Proteins Limits: Humans Language: En Year: 2004 Type: Article

Search on Google

XML

PubMed Links