Recruitment and expansion of dendritic cells in vivo potentiate the immunogenicity of plasmid DNA vaccines.

Sumida, Shawn M; McKay, Paul F; Truitt, Diana M; Kishko, Michael G; Arthur, Janelle C; Seaman, Michael S; Jackson, Shawn S; Gorgone, Darci A; Lifton, Michelle A; Letvin, Norman L; Barouch, Dan H

Sumida, Shawn M; McKay, Paul F; Truitt, Diana M; Kishko, Michael G; Arthur, Janelle C; Seaman, Michael S; Jackson, Shawn S; Gorgone, Darci A; Lifton, Michelle A; Letvin, Norman L; Barouch, Dan H.

Affiliation

Sumida SM; Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.

J Clin Invest ; 114(9): 1334-42, 2004 Nov.

Article in En | MEDLINE | ID: mdl-15520866

Subject(s)

Dendritic Cells/cytology; Immunotherapy/methods; Vaccines, DNA; Animals; Cancer Vaccines; Chemokine CCL3; Chemokine CCL4; Chemotaxis; Cytokines/metabolism; DNA, Viral; Dendritic Cells/metabolism; Enzyme-Linked Immunosorbent Assay; Epitopes/chemistry; HIV-1/genetics; Immunohistochemistry; Macrophage Inflammatory Proteins/metabolism; Membrane Proteins/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Plasmids/metabolism; Time Factors; Vaccinia virus/genetics

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Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Vaccines, DNA / Immunotherapy Limits: Animals Language: En Year: 2004 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Vaccines, DNA / Immunotherapy Limits: Animals Language: En Year: 2004 Type: Article