Abundant secretion of bioactive interleukin-1beta by human macrophages induced by Actinobacillus actinomycetemcomitans leukotoxin.

Kelk, P; Claesson, R; Hänström, L; Lerner, U H; Kalfas, S; Johansson, A

Kelk, P; Claesson, R; Hänström, L; Lerner, U H; Kalfas, S; Johansson, A.

Affiliation

Kelk P; Department of Odontology, University of Umeå, S-901 87 Umeå, Sweden.

Infect Immun ; 73(1): 453-8, 2005 Jan.

Article in En | MEDLINE | ID: mdl-15618184

Subject(s)

Aggregatibacter actinomycetemcomitans/pathogenicity; Exotoxins/pharmacology; Interleukin-1/metabolism; Macrophages/drug effects; Animals; Bone Resorption/etiology; Caspase 1/physiology; Dose-Response Relationship, Drug; Humans; Interleukin-6/biosynthesis; Macrophages/metabolism; Mice; RNA, Messenger/analysis; Tumor Necrosis Factor-alpha/biosynthesis

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Full text: 1 Database: MEDLINE Main subject: Interleukin-1 / Aggregatibacter actinomycetemcomitans / Exotoxins / Macrophages Type of study: Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Year: 2005 Type: Article

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