Deficient translocation of c-Rel is associated with impaired Th1 cytokine production in T cells from atopic dermatitis patients.

Dieckhoff, Karsten; Graf, Philipp; Beinhauer, Brigitte; Schwaerzler, Christoph; Carballido, José M; Neumann, Christine; Zachmann, Karolin; Jung, Thomas

Dieckhoff, Karsten; Graf, Philipp; Beinhauer, Brigitte; Schwaerzler, Christoph; Carballido, José M; Neumann, Christine; Zachmann, Karolin; Jung, Thomas.

Affiliation

Dieckhoff K; Department of Dermatology, University Goettingen, Germany.

Exp Dermatol ; 14(1): 17-25, 2005 Jan.

Article in En | MEDLINE | ID: mdl-15660915

Subject(s)

Cytokines/metabolism; Dermatitis, Atopic/immunology; Proto-Oncogene Proteins c-rel/metabolism; Th1 Cells/metabolism; Active Transport, Cell Nucleus/immunology; Adult; Antibodies, Monoclonal/pharmacology; CD28 Antigens/immunology; CD3 Complex/immunology; Cell Nucleus/immunology; Cell Nucleus/metabolism; Cell Proliferation; DNA/metabolism; Dermatitis, Atopic/blood; Humans; Interferon-gamma/metabolism; Interleukin-2/metabolism; Lymphocyte Activation/immunology; NF-kappa B/genetics; NF-kappa B/metabolism; Protein Binding; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-rel/genetics; T-Lymphocytes/drug effects; T-Lymphocytes/metabolism; Transcription Factor RelA; Transcription Factor RelB; Transcription Factors/metabolism

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Database: MEDLINE Main subject: Cytokines / Th1 Cells / Proto-Oncogene Proteins c-rel / Dermatitis, Atopic Type of study: Risk_factors_studies Limits: Adult / Humans Language: En Year: 2005 Type: Article

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