Cross-presentation by intercellular peptide transfer through gap junctions.

Neijssen, Joost; Herberts, Carla; Drijfhout, Jan Wouter; Reits, Eric; Janssen, Lennert; Neefjes, Jacques

Neijssen, Joost; Herberts, Carla; Drijfhout, Jan Wouter; Reits, Eric; Janssen, Lennert; Neefjes, Jacques.

Affiliation

Neijssen J; Division of Tumor Biology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. J.Neefjes@nki.nl

Nature ; 434(7029): 83-8, 2005 Mar 03.

Article in En | MEDLINE | ID: mdl-15744304

Subject(s)

Antigen Presentation/immunology; Antigen-Presenting Cells/immunology; Gap Junctions/metabolism; Peptides/immunology; Peptides/metabolism; T-Lymphocytes, Cytotoxic/immunology; T-Lymphocytes, Cytotoxic/metabolism; Antigen-Presenting Cells/cytology; Antigen-Presenting Cells/enzymology; Antigen-Presenting Cells/metabolism; Antigens, Viral/chemistry; Antigens, Viral/immunology; Antigens, Viral/metabolism; Bystander Effect/immunology; Cell Line, Tumor; Cells, Cultured; Connexin 43/genetics; Connexin 43/metabolism; Cytoplasm/enzymology; Diffusion; Fluoresceins/metabolism; Gap Junctions/chemistry; Gap Junctions/genetics; HLA-A2 Antigen/immunology; Humans; Molecular Weight; Monocytes/cytology; Monocytes/enzymology; Monocytes/immunology; Monocytes/metabolism; Orthomyxoviridae/immunology; Peptide Hydrolases/metabolism; Peptides/chemistry; Protein Transport; T-Lymphocytes, Cytotoxic/cytology; T-Lymphocytes, Cytotoxic/enzymology

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Database: MEDLINE Main subject: Peptides / T-Lymphocytes, Cytotoxic / Gap Junctions / Antigen Presentation / Antigen-Presenting Cells Limits: Humans Language: En Year: 2005 Type: Article

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