Development of antibodies that interfere with the collagen-VWF-GPIb axis as new antithrombotics.

Deckmyn, H; Cauwenberghs, N; Wu, D; Depraetere, H; Vanhoorelbeke, K

Deckmyn, H; Cauwenberghs, N; Wu, D; Depraetere, H; Vanhoorelbeke, K.

Affiliation

Deckmyn H; Laboratory for Thrombosis Research, KULeuven Campus Kortrijk, Interdisciplinary Research Center, E. Sabbelaan 53--B 8500 Kortrijk.

Verh K Acad Geneeskd Belg ; 67(1): 55-65, 2005.

Article in En | MEDLINE | ID: mdl-15828307

Subject(s)

Antibodies, Monoclonal/therapeutic use; Collagen/metabolism; Fibrinolytic Agents/therapeutic use; Platelet Glycoprotein GPIb-IX Complex/immunology; Thrombosis/prevention & control; von Willebrand Factor/immunology; Animals; Antibodies, Monoclonal/metabolism; Antigens/immunology; Collagen/immunology; Epitope Mapping; Fibrinolytic Agents/metabolism; Humans; Platelet Glycoprotein GPIb-IX Complex/metabolism; von Willebrand Factor/metabolism

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Database: MEDLINE Main subject: Thrombosis / Von Willebrand Factor / Collagen / Platelet Glycoprotein GPIb-IX Complex / Fibrinolytic Agents / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2005 Type: Article

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