The NF-kappaB pathway mediates fenretinide-induced apoptosis in SH-SY5Y neuroblastoma cells.

Hewson, Q D Campbell; Lovat, P E; Corazzari, M; Catterall, J B; Redfern, C P F

Hewson, Q D Campbell; Lovat, P E; Corazzari, M; Catterall, J B; Redfern, C P F.

Affiliation

Hewson QD; Northern Institute for Cancer Research and School of Clinical Medical Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, NE2 4HH, UK.

Apoptosis ; 10(3): 493-8, 2005 May.

Article in En | MEDLINE | ID: mdl-15909111

Subject(s)

Apoptosis/drug effects; Fenretinide/pharmacology; NF-kappa B/physiology; Flow Cytometry; Humans; I-kappa B Proteins/biosynthesis; NF-KappaB Inhibitor alpha; NF-kappa B/antagonists & inhibitors; Neuroblastoma; Phosphorylation; Reactive Oxygen Species/metabolism; Transfection; Tumor Cells, Cultured

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