Extracellular trypsin increases ASIC1a selectivity for monovalent versus divalent cations.

Neaga, Emil; Amuzescu, Bogdan; Dinu, Cristina; Macri, Beatrice; Pena, Florentina; Flonta, Maria-Luiza

Neaga, Emil; Amuzescu, Bogdan; Dinu, Cristina; Macri, Beatrice; Pena, Florentina; Flonta, Maria-Luiza.

Affiliation

Neaga E; Department of Biophysics and Physiology, Faculty of Biology, University of Bucharest, Splaiul Independentei 91-95, Bucharest 76201, Romania.

J Neurosci Methods ; 144(2): 241-8, 2005 Jun 15.

Article in En | MEDLINE | ID: mdl-15910984

Subject(s)

Cations, Divalent/metabolism; Cations, Monovalent/metabolism; Membrane Proteins/drug effects; Nerve Tissue Proteins/drug effects; Neurons, Afferent/drug effects; Neuropharmacology/methods; Sodium Channels/drug effects; Trypsin/pharmacology; Acid Sensing Ion Channels; Calcium/metabolism; Calcium/pharmacology; Calcium Signaling/drug effects; Calcium Signaling/physiology; Cell Line; Cell Membrane/chemistry; Cell Membrane/drug effects; Cell Membrane/metabolism; Cell Membrane Permeability/drug effects; Cell Membrane Permeability/physiology; Dose-Response Relationship, Drug; Extracellular Fluid/drug effects; Extracellular Fluid/metabolism; Humans; Hydrogen-Ion Concentration/drug effects; Membrane Potentials/drug effects; Membrane Potentials/physiology; Membrane Proteins/metabolism; Nerve Tissue Proteins/metabolism; Neurochemistry/methods; Neurons, Afferent/metabolism; Neurophysiology/methods; Patch-Clamp Techniques/methods; Sodium Channels/metabolism

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Database: MEDLINE Main subject: Neuropharmacology / Trypsin / Sodium Channels / Cations, Divalent / Cations, Monovalent / Membrane Proteins / Nerve Tissue Proteins / Neurons, Afferent Limits: Humans Language: En Year: 2005 Type: Article

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