Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma.

Ho, Joanna W Y; Man, Kwan; Sun, Chris K; Lee, Terence K; Poon, Ronnie T P; Fan, Sheung Tat

Ho, Joanna W Y; Man, Kwan; Sun, Chris K; Lee, Terence K; Poon, Ronnie T P; Fan, Sheung Tat.

Affiliation

Ho JW; Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Queen Mary Hospital, China.

Mol Cancer Ther ; 4(9): 1430-8, 2005 Sep.

Article in En | MEDLINE | ID: mdl-16170036

Subject(s)

Antineoplastic Agents, Hormonal/pharmacology; Carcinoma, Hepatocellular/blood supply; Carcinoma, Hepatocellular/drug therapy; Liver Neoplasms/blood supply; Liver Neoplasms/drug therapy; Neovascularization, Pathologic/prevention & control; Propylene Glycols/therapeutic use; Animals; Apoptosis/drug effects; Carcinoma, Hepatocellular/immunology; Cell Proliferation/drug effects; Endothelium, Vascular/cytology; Endothelium, Vascular/drug effects; Fingolimod Hydrochloride; Flow Cytometry; G1 Phase/drug effects; Humans; Liver Neoplasms/immunology; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microcirculation; Sphingosine/analogs & derivatives; Transplantation, Heterologous; Umbilical Veins/cytology; Umbilical Veins/drug effects; Wounds and Injuries

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Database: MEDLINE Main subject: Propylene Glycols / Carcinoma, Hepatocellular / Antineoplastic Agents, Hormonal / Liver Neoplasms / Neovascularization, Pathologic Limits: Animals / Humans / Male Language: En Year: 2005 Type: Article

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