Endogenous neuropeptide Y depresses the afferent signaling of gastric acid challenge to the mouse brainstem via neuropeptide Y type Y2 and Y4 receptors.

Wultsch, T; Painsipp, E; Thoeringer, C K; Herzog, H; Sperk, G; Holzer, P

Wultsch, T; Painsipp, E; Thoeringer, C K; Herzog, H; Sperk, G; Holzer, P.

Affiliation

Wultsch T; Department of Experimental and Clinical Pharmacology, Medical University of Graz, Universitätsplatz 4, A-8010 Graz, Austria.

Neuroscience ; 136(4): 1097-107, 2005.

Article in En | MEDLINE | ID: mdl-16216428

Subject(s)

Brain Stem/physiology; Gastric Acid/physiology; Gastric Mucosa/innervation; Neuropeptide Y/physiology; Receptors, Neuropeptide Y/physiology; Analysis of Variance; Animals; Arginine/analogs & derivatives; Arginine/pharmacology; Benzazepines/pharmacology; Brain Stem/cytology; Cell Count; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Transporter 3/metabolism; Female; Gastric Emptying; Gastric Mucosa/drug effects; Gastric Mucosa/pathology; Hydrochloric Acid/pharmacology; Hydrogen-Ion Concentration; Immunohistochemistry/methods; Mice; Mice, Knockout; Neurons/physiology; Peptide Fragments; Peptide YY/pharmacology; Proto-Oncogene Proteins c-fos/metabolism; Receptors, Neuropeptide Y/antagonists & inhibitors; Receptors, Neuropeptide Y/deficiency

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Full text: 1 Database: MEDLINE Main subject: Neuropeptide Y / Brain Stem / Receptors, Neuropeptide Y / Gastric Acid / Gastric Mucosa Limits: Animals Language: En Year: 2005 Type: Article

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