Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice.

Dumortier, Alexis; Jeannet, Robin; Kirstetter, Peggy; Kleinmann, Eva; Sellars, MacLean; dos Santos, Nuno R; Thibault, Christelle; Barths, Jochen; Ghysdael, Jacques; Punt, Jennifer A; Kastner, Philippe; Chan, Susan

Dumortier, Alexis; Jeannet, Robin; Kirstetter, Peggy; Kleinmann, Eva; Sellars, MacLean; dos Santos, Nuno R; Thibault, Christelle; Barths, Jochen; Ghysdael, Jacques; Punt, Jennifer A; Kastner, Philippe; Chan, Susan.

Affiliation

Dumortier A; Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS-INSERM-ULP, BP 10142, 67404 Illkirch, CU Strasbourg, France.

Mol Cell Biol ; 26(1): 209-20, 2006 Jan.

Article in En | MEDLINE | ID: mdl-16354692

Subject(s)

Basic Helix-Loop-Helix Transcription Factors/genetics; Homeodomain Proteins/genetics; Ikaros Transcription Factor/deficiency; Lymphoma, T-Cell/genetics; Receptor, Notch1/metabolism; Response Elements; Amino Acid Sequence; Animals; Cell Proliferation; Ikaros Transcription Factor/genetics; Mice; Molecular Sequence Data; Mutation; Promoter Regions, Genetic; Receptor, Notch1/genetics; Signal Transduction; Thymus Gland/metabolism; Thymus Gland/pathology; Transcription Factor HES-1

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Full text: 1 Database: MEDLINE Main subject: Lymphoma, T-Cell / Homeodomain Proteins / Response Elements / Basic Helix-Loop-Helix Transcription Factors / Ikaros Transcription Factor / Receptor, Notch1 Limits: Animals Language: En Year: 2006 Type: Article

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