Lipoteichoic acid-induced nitric oxide production depends on the activation of platelet-activating factor receptor and Jak2.

Han, Seung Hyun; Kim, Je Hak; Seo, Ho Seong; Martin, Michael H; Chung, Gook-Hyun; Michalek, Suzanne M; Nahm, Moon H

Han, Seung Hyun; Kim, Je Hak; Seo, Ho Seong; Martin, Michael H; Chung, Gook-Hyun; Michalek, Suzanne M; Nahm, Moon H.

Affiliation

Han SH; Department of Pathology, University of Alabama at Birmingham, AL 35294, USA.

J Immunol ; 176(1): 573-9, 2006 Jan 01.

Article in En | MEDLINE | ID: mdl-16365452

Subject(s)

Gram-Positive Bacterial Infections/immunology; Lipopolysaccharides/metabolism; Nitric Oxide/biosynthesis; Platelet Membrane Glycoproteins/metabolism; Protein-Tyrosine Kinases/metabolism; Proto-Oncogene Proteins/metabolism; Receptors, G-Protein-Coupled/metabolism; Teichoic Acids/metabolism; Animals; Enzyme Inhibitors/pharmacology; Janus Kinase 2; Lipopolysaccharides/immunology; Macrophages/immunology; Macrophages/metabolism; Mice; Peptides/metabolism; Platelet Membrane Glycoproteins/immunology; Protein-Tyrosine Kinases/drug effects; Protein-Tyrosine Kinases/immunology; Proto-Oncogene Proteins/drug effects; Proto-Oncogene Proteins/immunology; Receptors, G-Protein-Coupled/immunology; STAT1 Transcription Factor/drug effects; STAT1 Transcription Factor/immunology; STAT1 Transcription Factor/metabolism; Teichoic Acids/immunology; Tumor Necrosis Factor-alpha/biosynthesis; Tumor Necrosis Factor-alpha/drug effects

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Full text: 1 Database: MEDLINE Main subject: Teichoic Acids / Protein-Tyrosine Kinases / Platelet Membrane Glycoproteins / Lipopolysaccharides / Proto-Oncogene Proteins / Gram-Positive Bacterial Infections / Receptors, G-Protein-Coupled / Nitric Oxide Limits: Animals Language: En Year: 2006 Type: Article

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