cAMP-dependent phosphorylation of PTB1 promotes the expression of insulin secretory granule proteins in beta cells.

Knoch, Klaus-Peter; Meisterfeld, Ronny; Kersting, Stephan; Bergert, Hendrik; Altkrüger, Anke; Wegbrod, Carolin; Jäger, Melanie; Saeger, Hans-Detlev; Solimena, Michele

Knoch, Klaus-Peter; Meisterfeld, Ronny; Kersting, Stephan; Bergert, Hendrik; Altkrüger, Anke; Wegbrod, Carolin; Jäger, Melanie; Saeger, Hans-Detlev; Solimena, Michele.

Affiliation

Knoch KP; Laboratory of Experimental Diabetology, Medical School, Dresden University of Technology, Fetscherstrasse 74, 01307 Dresden, Germany.

Cell Metab ; 3(2): 123-34, 2006 Feb.

Article in En | MEDLINE | ID: mdl-16459313

Subject(s)

Cyclic AMP/metabolism; Gene Expression Regulation/physiology; Insulin-Secreting Cells/metabolism; Insulin/biosynthesis; Muscle Proteins/metabolism; RNA-Binding Proteins/metabolism; Animals; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases/metabolism; DNA Primers; DNA, Complementary/genetics; Female; Glucagon-Like Peptide 1/metabolism; Glucose/metabolism; Heterogeneous-Nuclear Ribonucleoproteins; Immunohistochemistry; Luciferases; Muscle Proteins/genetics; Phosphorylation; Polypyrimidine Tract-Binding Protein; RNA Interference; RNA-Binding Proteins/genetics; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Secretory Vesicles/metabolism

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Database: MEDLINE Main subject: Gene Expression Regulation / RNA-Binding Proteins / Cyclic AMP / Insulin-Secreting Cells / Insulin / Muscle Proteins Type of study: Prognostic_studies Limits: Animals Language: En Year: 2006 Type: Article

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