A presenilin-1 mutation (T245P) in transmembrane domain 6 causes early onset Alzheimer's disease.

Edwards-Lee, Terri; Wen, Johnny; Bell, Jason; Hardy, John; Chung, Julia; Momeni, Parastoo

Edwards-Lee, Terri; Wen, Johnny; Bell, Jason; Hardy, John; Chung, Julia; Momeni, Parastoo.

Affiliation

Edwards-Lee T; Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, 1124 West Carson Street, Torrance, CA 90502, USA.

Neurosci Lett ; 398(3): 251-2, 2006 May 08.

Article in En | MEDLINE | ID: mdl-16469444

Subject(s)

Alzheimer Disease/genetics; Membrane Proteins/genetics; Adult; Age of Onset; Amnesia/genetics; Female; Humans; Male; Middle Aged; Mutation; Pedigree; Presenilin-1; Protein Structure, Tertiary

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Database: MEDLINE Main subject: Alzheimer Disease / Membrane Proteins Type of study: Etiology_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2006 Type: Article

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