Mutation Glu82Lys in lamin A/C gene is associated with cardiomyopathy and conduction defect.

Wang, Hu; Wang, Jizheng; Zheng, Weiyue; Wang, Xiaojian; Wang, Shuxia; Song, Lei; Zou, Yubao; Yao, Yan; Hui, Rutai

Wang, Hu; Wang, Jizheng; Zheng, Weiyue; Wang, Xiaojian; Wang, Shuxia; Song, Lei; Zou, Yubao; Yao, Yan; Hui, Rutai.

Affiliation

Wang H; Sino-German Laboratory for Molecular Medicine, Fuwai Cardiovascular Hospital and Cardiovascular Institute, Peking Union Medical College and Chinese Academy of Medical Sciences, 167 Beilishi Road, 100037 Beijing, China.

Biochem Biophys Res Commun ; 344(1): 17-24, 2006 May 26.

Article in En | MEDLINE | ID: mdl-16630578

Subject(s)

Cardiomyopathy, Dilated/genetics; Heart Block/genetics; Heart Conduction System/physiopathology; Lamin Type A/genetics; Lamin Type A/metabolism; Adult; Amino Acid Sequence; Amino Acid Substitution; Asian People/genetics; Cardiomyopathy, Dilated/metabolism; Cell Nucleus/chemistry; Cell Nucleus/genetics; Cell Nucleus/ultrastructure; Cells, Cultured; Child; Female; Glutamic Acid/chemistry; Glutamic Acid/genetics; Heart Block/metabolism; Humans; Lamin Type A/analysis; Lysine/chemistry; Lysine/genetics; Male; Membrane Proteins/analysis; Membrane Proteins/metabolism; Molecular Sequence Data; Nuclear Envelope/chemistry; Nuclear Envelope/ultrastructure; Nuclear Proteins; Pedigree; Point Mutation; Thymopoietins/analysis; Thymopoietins/metabolism

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Database: MEDLINE Main subject: Cardiomyopathy, Dilated / Lamin Type A / Heart Block / Heart Conduction System Type of study: Risk_factors_studies Limits: Adult / Child / Female / Humans / Male Language: En Year: 2006 Type: Article

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