Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer.

Dahl, Edgar; Kristiansen, Glen; Gottlob, Kathrin; Klaman, Irina; Ebner, Elke; Hinzmann, Bernd; Hermann, Klaus; Pilarsky, Christian; Dürst, Matthias; Klinkhammer-Schalke, Monika; Blaszyk, Hagen; Knuechel, Ruth; Hartmann, Arndt; Rosenthal, André; Wild, Peter J

Dahl, Edgar; Kristiansen, Glen; Gottlob, Kathrin; Klaman, Irina; Ebner, Elke; Hinzmann, Bernd; Hermann, Klaus; Pilarsky, Christian; Dürst, Matthias; Klinkhammer-Schalke, Monika; Blaszyk, Hagen; Knuechel, Ruth; Hartmann, Arndt; Rosenthal, André; Wild, Peter J.

Affiliation

Dahl E; Institute of Pathology, University Hospital of the RWTH Aachen, Aachen, Germany. edahl@ukaachen.de

Clin Cancer Res ; 12(13): 3950-60, 2006 Jul 01.

Article in En | MEDLINE | ID: mdl-16818692

Subject(s)

Biomarkers, Tumor/genetics; Breast Neoplasms; Carcinoma, Ductal, Breast; Gene Expression Profiling; Lasers; Microdissection/methods; alpha Karyopherins/genetics; Breast Neoplasms/diagnosis; Breast Neoplasms/enzymology; Breast Neoplasms/genetics; Carcinoma, Ductal, Breast/diagnosis; Carcinoma, Ductal, Breast/enzymology; Carcinoma, Ductal, Breast/genetics; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunohistochemistry; Middle Aged; Multivariate Analysis; Neoplasm Staging; Phosphatidate Phosphatase/genetics; Prognosis; RNA/genetics; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction/methods; Sulfotransferases/genetics; Survival Rate; Tissue Array Analysis/methods; Up-Regulation/genetics

Search on Google

XML

PubMed Links

Database: MEDLINE Main subject: Breast Neoplasms / Biomarkers, Tumor / Carcinoma, Ductal, Breast / Gene Expression Profiling / Alpha Karyopherins / Microdissection / Lasers Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Female / Humans / Middle aged Language: En Year: 2006 Type: Article

Search on Google

XML

PubMed Links